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This protein slows the aging brain and we know how to counter it

Wed, 20 Aug 2025 07:32:10 +0200

Aging is particularly harsh on the hippocampus — the brain region responsible for learning and memory. Now, researchers at UC San Francisco have identified a protein that’s at the center of this decline. They looked at how the genes and proteins in the hippocampus changed over time in mice and foun...

Sensing sour: How SNAP25 powers taste signals and keeps sensory cells alive

Wed, 20 Aug 2025 07:32:09 +0200

The tongue contains numerous taste buds—tiny sensory organs responsible for detecting taste. Taste buds consist of specialized cells that translate chemical stimuli into neural signals. Among them, type II cells, which respond to sweet, umami, and bitter stimuli, utilize channel-based signal transmi...

Stora Enso’s billion-euro investment in renewable packaging

Wed, 20 Aug 2025 07:32:01 +0200

The largest and most modern consumer packaging board production line in Europe was inaugurated in Oulu, Finland. The new line was inaugurated by Prime Minister of Finland Petteri Orpo, Chair of Stora Enso’s Board of Directors Kari Jordan, President and CEO of Stora Enso Hans Sohlström, and Oulu mill...

The diamonds that could find cancer

Wed, 20 Aug 2025 07:32:00 +0200

University of Warwick researchers have built a new diamond-based magnetic field sensor that could be used to better find tumours through tracing magnetic fluid injected in the body. A cancer diagnosis is most problematic when cells from the tumour have metastasised (spread) to other organs. This mo...

Using bacteria to sneak viruses into tumors

Tue, 19 Aug 2025 07:32:03 +0200

Researchers at Columbia Engineering have built a cancer therapy that makes bacteria and viruses work as a team. In a study published in Nature Biomedical Engineering, the Synthetic Biological Systems Lab shows how their system hides a virus inside a tumor-seeking bacterium, smuggles it past the immu...

Ultrasound could deliver drugs with fewer side effects

Tue, 19 Aug 2025 07:32:01 +0200

The trouble with many drugs is that they go where they shouldn’t, producing unwanted side effects. Psychiatric drugs might cause dissociation, painkillers can induce nausea and chemotherapy often damages healthy cells. Now a team of Stanford Medicine researchers are closing in on a novel solution: a...

Insights into olfactory disorders in Alzheimer's disease

Tue, 19 Aug 2025 07:31:59 +0200

A diminishing sense of smell can be one of the earliest signs of Alzheimer's disease, even before cognitive impairment occurs. Studies by researchers at the DZNE and Ludwig-Maximilians-Universität München (LMU) provide new insights into this phenomenon. According to the study, the brain's immune res...

Reduced genome – flexible performance: How symbiotic bacteria with minimal genetic information support their host

Mon, 18 Aug 2025 07:32:03 +0200

Many insects live in symbiosis with certain species of bacteria. These bacteria make important contributions to their hosts' nutrition, digestion, detoxification, reproduction and defense. Due to their close coexistence with insects, symbionts often lose genes for metabolic products that are also pr...

New method loads mRNA into exosomes in 10 minutes—just mix and go

Mon, 18 Aug 2025 07:32:01 +0200

Exosomes, naturally derived vesicles responsible for intercellular communication, are emerging as next-generation drug delivery systems capable of transporting therapeutics to specific cells. However, their tightly packed, cholesterol-rich membranes make it extremely difficult to encapsulate large m...

Innovative treatment for liver tumors: Electrochemotherapy (ECT) at the University Hospital Regensburg

Mon, 18 Aug 2025 07:31:59 +0200

The University Hospital Regensburg (UKR) is setting new standards in the treatment of liver tumors: With electrochemotherapy (ECT), the Institute of Diagnostic Radiology at the UKR offers a promising, gentle and minimally invasive treatment option for patients with primary or secondary liver tumors....

Head-to-head against AI, pharmacy students won

Fri, 15 Aug 2025 07:32:05 +0200

Students pursuing a Doctor of Pharmacy degree routinely take – and pass – rigorous exams to prove competency in several areas. Can ChatGPT accurately answer the same questions? A new study by University of Arizona R. Ken Coit College of Pharmacy researchers said no, it can’t. Researchers found that ...

Researchers discover previously unknown "mini-factories" for protein folding

Fri, 15 Aug 2025 07:32:04 +0200

In order for proteins to perform their many functions, they must be folded correctly. A research team at the University of Basel has now discovered a type of "folding factory" in which proteins are folded efficiently and without errors. If these factories are missing, this can lead to diseases such ...

Norgine completes acquisition of Theravia

Fri, 15 Aug 2025 07:32:01 +0200

Norgine announced the successful completion of the acquisition of Theravia, an international pharmaceutical company specializing in therapies for patients with rare and serious diseases. The completion of this acquisition is an important step for Norgine towards its goal of bringing life-changing me...

Dr. Wolf-Henning Walther becomes new CEO at Metrohm Germany

Fri, 15 Aug 2025 07:32:00 +0200

Dr. Wolf-Henning Walther will take over as Managing Director of Metrohm Deutschland GmbH & Co. KG on September 1, 2025 and will form the Executive Board together with Michael Feige and Dr. Volker Frost. Frank Rückle, the current Managing Director, will take his well-deserved retirement on September ...

How immune cells switch into attack mode

Thu, 14 Aug 2025 07:32:06 +0200

Fighting off pathogens is a tour de force that must happen with speed and precision. A team of researchers at CeMM and MedUni Vienna led by Christoph Bock and Matthias Farlik has investigated how macrophages—immune cells that are the body’s first responders—master this challenge. Their study offers ...

When the reflection kills

Thu, 14 Aug 2025 07:32:04 +0200

In nature, there are often substances that behave like mirror images, such as the well-known left- and right-turning lactic acid. Research teams from the University of Marburg and the University of Geneva have now discovered how the growth of certain cancer cells can be specifically weakened with a ...

AI Meets CRISPR for Precise Gene Editing

Thu, 14 Aug 2025 02:00:00 +0200

A research team headed by the University of Zurich has developed a powerful new method to precisely edit DNA by combining cutting-edge genetic engineering with artificial intelligence. This technique opens the door to more accurate modeling of human diseases and lays the groundwork for next-generati...

Structural basis of the function of therapeutic antibodies in cancer immunotherapy elucidated

Wed, 13 Aug 2025 14:50:59 +0200

Therapeutic antibodies have revolutionized cancer treatment, but the exact molecular mechanisms that determine their therapeutic effect have so far been insufficiently investigated. A team led by Professor Ralf Jungmann (Chair of Molecular Physics of Life at LMU and head of the Molecular Imaging and...

Lost in translation: New vulnerability of the aging brain discovered

Wed, 13 Aug 2025 07:32:11 +0200

Proteostasis describes the balance of proteins in cells, which includes the continuous production of new proteins, their correct folding, and the degradation of damaged or redundant proteins. This balance is essential for cell health; if it is out of balance, misfolded or redundant proteins can accu...

Biomarkers for Brain Insulin Resistance Discovered in the Blood

Wed, 13 Aug 2025 07:32:09 +0200

If the brain no longer responds properly to insulin (insulin resistance), this can lead to overweight, diabetes, and Alzheimer's disease. Researchers at the German Center for Diabetes Research (DZD) in Potsdam and Tübingen have discovered small chemical modifications to genetic material (epigenetic ...

Milestone for medical research: New method enables comprehensive identification of omega fatty acids

Wed, 13 Aug 2025 07:32:03 +0200

Omega-3 fatty acids are known to be an essential part of a healthy diet. As humans cannot produce them, they have to be consumed in sufficient amounts. However, omega-6, -7, -9, and -10 fatty acids also play important roles in the metabolism of fats. These numbers indicate the position of the first ...

Mobile science for a planet in transition

Tue, 12 Aug 2025 07:32:11 +0200

With funding from the Klaus Tschira Foundation, the European Molecular Biology Laboratory (EMBL) is ushering in a new era of field-based molecular life sciences. On scientific expeditions throughout Europe, mobile laboratories will investigate freshwater ecosystems and the pressures placed on them b...

Excessive ultraprocessed foods (UPFs) and poor nutrition tied to poor health

Tue, 12 Aug 2025 07:32:06 +0200

Ultraprocessed foods or UPFs are a growing concern due to their widespread consumption and impact on potential health risks. Most UPFs, particularly those commonly seen in U.S. dietary patterns, are high in saturated fat, added sugars and sodium (salt), the combination of which is often abbreviated ...

Dana-Farber Cancer Institute unveils groundbreaking blood test for multiple myeloma

Tue, 12 Aug 2025 07:32:04 +0200

Researchers at Dana-Farber Cancer Institute have developed a blood test that could transform the diagnosis and monitoring of multiple myeloma (MM) and its precursor conditions. The new method, known as SWIFT-seq, utilizes single-cell sequencing to profile circulating tumor cells (CTCs) in the blood,...

Researchers identify a potential biomarker for long COVID

Tue, 12 Aug 2025 07:32:02 +0200

Researchers from the Translational Genomics Research Institute (TGen), part of City of Hope, and the Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center have identified a potential biomarker for long COVID. If the findings of their study are confirmed by other research center...

Cannovum Health welcomes new strategic majority investor

Tue, 12 Aug 2025 02:00:00 +0200

Cannovum Health GmbH celebrates a key milestone in its corporate development: Triple Crown Ventures becomes the new majority investor. With this step, the company gains a financially strong and strategic partner who firmly believes in Cannovum Health’s vision. In addition to increasing Cannovum Heal...

CureVac Announces Resolution of Patent Litigation with Pfizer/BioNTech

Mon, 11 Aug 2025 07:32:14 +0200

CureVac N.V. announced that CureVac N.V. and an affiliate (together, “CureVac”), and an affiliate of GSK plc have entered into agreements with BioNTech SE and an affiliate (together, “BioNTech”) and Pfizer, Inc. to resolve and dismiss all pending patent litigation in the United States between the co...

Could lithium explain — and treat — Alzheimer’s disease?

Mon, 11 Aug 2025 07:32:11 +0200

What is the earliest spark that ignites the memory-robbing march of Alzheimer’s disease? Why do some people with Alzheimer’s-like changes in the brain never go on to develop dementia? These questions have bedeviled neuroscientists for decades. Now, a team of researchers at Harvard Medical School may...

WACKER and start-up Gearbox Biosciences announce strategic collaboration

Mon, 11 Aug 2025 02:00:00 +0200

Wacker Chemie AG and OÜ Gearbox Biosciences announced a strategic collaboration. Gearbox Biosciences, based in Estonia, are pioneers in the antibiotic-free microbial production of biologics. This partnership aims to co-develop technologies that will revolutionize the manufacturing of pDNA, the criti...

A Patch for the Heart

Fri, 08 Aug 2025 07:32:04 +0200

A new type of tissue-engineered cardiac patch could not only seal defective areas of the heart, as has been the case up to now, but also heal them. An interdisciplinary team led by ETH Zurich has successfully implanted the patch in animals. Following a heart attack, blood flow to the heart is interr...

Potatoes may increase risk of type 2 diabetes

Fri, 08 Aug 2025 07:32:01 +0200

French fries were associated with an increased risk of developing type 2 diabetes (T2D), while other forms of potatoes—including baked, boiled, and mashed—were not, according to a new study led by Harvard T.H. Chan School of Public Health. The study also found that swapping any form of potato for wh...

Merck Delivers Profitable Organic Growth Amid Strong Currency Headwinds

Fri, 08 Aug 2025 02:00:00 +0200

Merck, a leading science and technology company, continues its organic growth. Despite ongoing geopolitical uncertainties, Group net sales in the second quarter of 2025 increased by 2.0% organically compared with the year-earlier quarter, while EBITDA pre rose by 4.6% organically. Process Solutions ...

Playing Dominos: How an Artificial Protein Emerges from Fitting Together Individual Components

Thu, 07 Aug 2025 07:32:10 +0200

The targeted engineering of artificial proteins with unique properties – that is possible with the assistance of a novel method developed by a research team led by Prof. Dr Dominik Niopek at the Institute of Pharmacy and Molecular Biotechnology (IPMB) of Heidelberg University. It centers around a ne...

Beyond classic stress signalling: how mitochondrial stress softens the cell nucleus and alters cellular identity

Thu, 07 Aug 2025 07:32:02 +0200

A University of Cologne research team has discovered that cells in high-energy-demanding tissues respond to mitochondrial dysfunction in a surprising way. Instead of shutting down, cells adjust their metabolism to produce a particular molecule, which alters the mechanics of the cell nucleus to cope ...

Bayer posts positive second quarter and progress on strategic priorities

Thu, 07 Aug 2025 02:00:00 +0200

The Bayer Group is on track following an encouraging first half of the year. “We’re beginning an important second half of 2025, which will be marked by further progress on all strategic priorities, continued launches, and geopolitical and currency crosswinds to navigate,” CEO Bill Anderson said when...

An advanced imaging technique detects cancer with unprecedented precision

Thu, 07 Aug 2025 02:00:00 +0200

Researchers from Helmholtz Munich, the Technical University of Munich (TUM), and the Medical University of Vienna have developed an advanced imaging technique called "O2E" that allows clinics to detect cancerous lesions in the esophagus with unprecedented precision. Published in Nature Biomedical En...

Left-handed or right-handed? Nanostructures identified by light

Wed, 06 Aug 2025 07:32:08 +0200

How do left-handed and right-handed molecules differ? Researchers at ETH Zurich are using a new imaging method to visualise what was previously only measurable as an average, opening up new possibilities for biology and materials science. Why do spearmint and caraway seeds smell so differently, alth...

Engineered enzyme to precisely build complex molecules

Wed, 06 Aug 2025 07:32:05 +0200

Researchers at the University of Basel have repurposed a natural enzyme so that it catalyzes a highly challenging chemical reaction. Their approach opens new possibilities for synthesizing complex molecules—such as pharmaceuticals and fine chemicals—in a more environmentally friendly and efficient w...

When eating is a burden

Wed, 06 Aug 2025 07:32:02 +0200

People with the eating disorder ARFID severely restrict their food intake in terms of quantity or variety - this leads to physical and psychological impairments. The disorder usually begins in childhood and has so far mainly been studied in children or people who are underweight. A new study by Leip...

New Discovery in Enzyme Research: Water is the Key for Activity

Wed, 06 Aug 2025 02:00:00 +0200

Researchers from the University of Greifswald have discovered a special feature of enzymes that play a role in the conversion of sugar molecules. They identified a precisely coordinated water molecule. In the long run, this discovery could help to enhance the use of biocatalysts in industrial applic...

Shaping the future of mRNA based drug delivery

Tue, 05 Aug 2025 07:32:09 +0200

A team from the Max-Planck-Institut für Kohlenforschung, Hokkaido University, and Osaka University has discovered that subtle differences in molecular structure can have a major impact on the performance of mRNA-based drugs. Their findings, published in the Journal of the American Chemical Society, ...

A Less Debilitating Approach to Cancer Diagnosis

Tue, 05 Aug 2025 07:32:07 +0200

Imaging methods are an essential part of medicine, used in everything from diagnosis and treatment to follow-up examinations. X-ray mammography dominates the field of early detection of breast cancer, providing rapid and accurate two-dimensional images. Three-dimensional computed tomography (CT) is ...

From Pollutant to Valuable Chemical Product

Tue, 05 Aug 2025 07:32:01 +0200

In two studies that have just been published in the renowned journal Nature Catalysis, the research teams show how the two nickel-containing enzymes carbon monoxide dehydrogenase (CODH) and acetyl-CoA synthase (ACS) transform CO2 into activated acetic acid. These detailed insights into the mechanism...

Humify – superfood for the soil

Tue, 05 Aug 2025 02:00:00 +0200

Hot and humid temperatures, no light, no air and then that intense odour: when the high-pressure cooker is fired up in the start-up Humify's laboratory, it is hard to imagine that under such conditions the resulting product – a kind of black liquid sludge – could help to influence climate change and...

€12M for LIfT BioSciences: Breakthrough in Cancer Therapy?

Tue, 05 Aug 2025 02:00:00 +0200

LIfT BioSciences a rapidly emerging biotech and the global leader in neutrophil immunotherapies, announces a grant of €12 million has been awarded from Ireland’s Disruptive Technologies Innovation Fund (DTIF) to advance its Immuno-Modulatory Alpha Neutrophils (IMANs), designed to overcome treatment ...

Heavy drinking raises the risk of undesired pregnancy

Mon, 04 Aug 2025 07:32:05 +0200

A new study has found that, among women with a high desire to avoid becoming pregnant, those who drank heavily had a 50% higher risk of becoming pregnant than those who drank moderately or not at all. In contrast, participants who used cannabis were no more likely to have an undesired pregnancy than...

Labguru and Titian Software Rebrand as Cenevo

Mon, 04 Aug 2025 07:32:01 +0200

Titian Software and Labguru have rebranded as Cenevo, bringing together the two companies’ solutions, Labguru and Mosaic, under a new, unified brand, to enable further innovation and increased collaboration to accelerate scientific discovery. The combined organization specializes in lab management s...

PL BioScience Announces Major Site Expansion

Mon, 04 Aug 2025 02:00:00 +0200

PL BioScience GmbH, a German life science company specializing in the production and development of Human Platelet Lysate (HPL) for cell expansion, announced a significant expansion of company headquarters and future manufacturing capabilities to meet the rapidly growing global demand for safe, anim...

Where science powers start-ups

Mon, 04 Aug 2025 02:00:00 +0200

TUM Venture Labs, BioLabs and Eli Lilly and Company (Lilly) launched BioLabs|TUM, a new biotechnology innovation hub in central Munich. The initiative aims to empower early-stage biotech start-ups by providing access to state-of-the-art lab infrastructure, expert mentoring, and global industry netwo...

Sanofi to acquire biotech start-up Vicebio

Mon, 04 Aug 2025 02:00:00 +0200

Sanofi announces it has entered into an agreement to acquire Vicebio Ltd, a privately held biotechnology company headquartered in London, UK. The acquisition brings an early-stage combination vaccine candidate for respiratory syncytial virus (RSV) and human metapneumovirus (hMPV), both respiratory v...

Air bubble-free chromatography on a pilot scale

Sun, 17 Aug 2025 04:00:00 +0200

YMC PilotPLUS columns are completely biocompatible and characterised by safe and easy handling. Packing, operating and unpacking the column are quick and reproducibly performed due to a number of significant advantages. With the handy infilling assistance tool the slurry can be transferred into the ...

Eppendorf incubator shakers - your solution in the 2023/24 catalogue

Sun, 17 Aug 2025 04:00:00 +0200

Are you looking for a reliable incubator shaker for your solubility studies, bioreactor inoculum preparation, parallel screening, growth of phototropic organisms, or production of peptides, recombinant proteins, enzymes and other products? Discover the large portfolio of Innova and New Brunswick sha...

Analysis of particle size and particle shape in laboratory and process from below 1 µm to 34,000 µm

Thu, 14 Aug 2025 04:00:00 +0200

Sympatec's image analysis sensor combines particle size and shape analysis. The particle analyzer QICPIC determines particle sizes between 1 µm and 30 mm....

Particle Size and Particle Size Distribution in Laboratory and Process from below 0.1 µm to 8,750 µm

Thu, 14 Aug 2025 04:00:00 +0200

HELOS: Particle Size Analysis from 0.1 µm to 8,750 µm with up to 217 measuring points for particle size distribution analysis of powders, aerosols, sprays, suspensions and other particulate systems...

Formalin-free ready-to-use solution for the fixation of histological preparations

Fri, 01 Aug 2025 04:00:00 +0200

ROTI®Histofix ECO Plus is a ready-to-use aqueous solution that can be used as a sustainable alternative to formaldehyde for tissue fixation. The solution is based on hexamethylenetetramine and has a pH value of 4.5 to 5.0. In contrast to the classic formalin solution, ROTI®Histofix ECO Plus is not c...

Ready-to-use, color-coded buffer solutions for precise calibration of pH meters

Fri, 01 Aug 2025 04:00:00 +0200

Carl ROTH offers a comprehensive range of calibration and control standards for the precise and fast calibration of measuring devices such as pH meters. The ready-to-use solutions can be used directly, eliminating the time-consuming drying and weighing of reagents for self-prepared solutions. ROTI®C...

The Versatile Particle and Dispersion Analyser: At-Line, in the Process and in the Laboratory

Tue, 29 Jul 2025 04:00:00 +0200

The analytical instruments made by L.U.M. GmbH for fast stability analysis of high concentrated emulsions and suspensions and particle characterization...

Ultra-compact microspectrometer for versatile applications

Mon, 28 Jul 2025 04:00:00 +0200

Find Hamamatsu's product range of small components like highly sensitive photomultipliers, photodiodes as well as micro-spectrometers and mini-spectrometer...

Raise your benchmark with ÄKTA pure chromatography system

Sun, 27 Jul 2025 04:00:00 +0200

ÄKTA pure lab-scale chromatography systems: Speed, performance, and flexibility. Designed for the efficient purification of biomolecules, ÄKTA systems are ideal for both research and process development. With their intelligent UNICORN system control software, ÄKTA systems combine simplicity with pow...

Efficient protein purification on a laboratory scale

Sat, 26 Jul 2025 04:00:00 +0200

ÄKTA™ systems are thoughtfully designed to meet the diverse needs of biomolecule purification, delivering exceptional speed, performance, and flexibility across research and process development stages. Utilizing the intelligent UNICORN™ system control software, ÄKTA™ systems seamlessly combine simpl...

Automated cell counting – fast and efficient

Fri, 18 Jul 2025 04:00:00 +0200

The EVE Plus automated cell counter fully replaces laborious manual counting under the microscope, offering significantly enhanced accuracy, objectivity, and reproducibility in cell analysis. With proven staining methods such as trypan blue or erythrosin B, the device reliably determines total cell ...

Automated cell counting for fast and reliable cell characterization

Fri, 18 Jul 2025 04:00:00 +0200

The automated cell counters ADAM MCPlus and CellTPlus help users make the entire cell counting process faster, more efficient, and more reliable. With their low sample volume, they conserve valuable resources and enable frequent, simple analyses – a major advantage in dynamic laboratory environments...

Innovation in sample preparation thanks to adjustable pipetting heads

Thu, 17 Jul 2025 04:00:00 +0200

The CyBio Well vario is a pipetting platform that offers high precision and flexibility. It can meet your pipetting needs with different pipetting heads and a wide volume range. The CyBio Well vario is equipped with a wide range of accessories and adapts to any screening environment. Thanks to air d...

Protein purification made easy with Cytiva manuals

Thu, 17 Jul 2025 04:00:00 +0200

Cytiva’s Life Sciences business offers principles and methodology handbooks covering a wide range of techniques and applications including sample preparation, protein purification, electrophoresis, blotting, and cell culture. Whether you’re a beginner or an expert, our handbooks are a great referenc...

Semi-automatic pipetting station for maximum accuracy

Thu, 17 Jul 2025 04:00:00 +0200

CyBio SELMA is a semi-automatic pipettor for laboratories that takes over your daily pipetting tasks. With this compact pipetting station, you can process 96- and 384-well microplates quickly and precisely without the need for complex programming. Operation is intuitive and takes place via user-guid...

Real-Time Characterization of Particles and Dispersions in Micro and Nano Range in Colani Design

Wed, 16 Jul 2025 04:00:00 +0200

The new multi-wavelength LUMiReader®PSA, developed by LUM GmbH and ergonomically designed by Luigi Colani, determines diverse properties of particles, emulsions and suspension in the micro and nanoscope in real time. Particle size distribution weighted by volume and number based on ISO 13317 Volume...

Automated high-throughput cell counting for maximum efficiency and precision

Fri, 11 Jul 2025 02:00:00 +0200

The Nanoentek EVE™ HT FL cell counter is the ideal solution for laboratories that value efficiency, precision, and standardization in cell counting. Designed specifically for use in research and production-related laboratory environments, this device impresses with its fully automated operation. Wit...

Turnkey biobank for the cryopreservation of biological samples

Mon, 07 Jul 2025 02:00:00 +0200

Consarctic cryobanks and cryostorage systems stand for quality, expertise, innovation and reliability for decades. We offer our customers individual solutions, starting with consulting, design, planning, delivery, installation and commissioning (IQ/OQ) of turnkey cryostorage systems. In addition, we...

Green Line: Accurate and sustainable temperature control systems for laboratories and industry

Tue, 01 Jul 2025 04:00:00 +0200

The original, reworked! Peter Huber Kältemaschinenbau SE has revised the Unistat temperature control systems and expanded them with the latest technologies. The concept, which has been established for decades, is now even more efficient and sustainable and offers a 4-year guarantee. Numerous models ...

UV/Vis measurements for microplates and cuvettes in the blink of an eye

Mon, 30 Jun 2025 04:00:00 +0200

Nano - ultrafast spectrometer for microplates, cuvettes and low volume samples" src="https://img.chemie.de/Portal/Products/148402_f4XXL5C0f.jpg?tr=n-xzoom" />
Absorbance meter for microtiter plates and cuvettes ✓ from 0.3 µl sample volume ✓ less 1s measuring time/well ✓ Up to 900 data points per well ✓ Robot compatible...

Multiparameter measurement redefined – your new all-in-one solution

Tue, 15 Jul 2025 04:00:00 +0200

water expertise ISO Certified Our Brands 4 SOUR* 5 simultaneously - no need to change electrodes. Simple plug- and-play operation and built-in Part 11. The MultiLab? has strict user management, an audit trail, password management and data testing. Fully ? Xylem Trial-Version The customer can test an...

An exciting new eBook: AFM in the Life Sciences

Tue, 17 Jun 2025 04:00:00 +0200

EB2001 Rev. A0 Super-Resolution e-book Foreword ............................................................................... 4 Introduction .......................................................................... 5 Origins of Microscopy for Biological Sciences .............................. 5 C...

Artificial Intelligence in the Life Sciences Industry

Mon, 12 May 2025 04:00:00 +0200

Slide 4: 2. Life Sciences & AI Slide 5: 2. Life Sciences & AI Slide 6: 2. Life Sciences & AI Slide 7: 3. Overview on AI Slide 8: 3. Overview on AI Slide 9: 4. Drug Discovery Slide 10: 4. Drug Discovery Slide 11: 4. Drug Discovery Slide 12: 5. Exploratory Development Slide 13: 5. Exploratory Developm...

Data Integrity, Compliance and Weighing Excellence while Saving Time

Thu, 08 May 2025 04:00:00 +0200

Editorial Article: Cubis II and Starlims Data ComplianceWith time a precious commodity and ever-increasing regulatory scrutiny, pharmaceutical laboratories are always on the lookout for simple solutions to make their routine tasks easier. Here, we speak with experts Dr. Andreas Sch?ler, technical sa...

Building Credibility into Scientific Research and Pharmaceutical Manufacturing

Thu, 08 May 2025 04:00:00 +0200

The Path to Rock-Solid Data Integrity Building Credibility into Scientific Research and Pharmaceutical Manufacturing Data integrity is crucial for achieving reliable outcomes. It supports regulatory compliance, product quality, and ultimately, patient safety. What is Data Integrity? Modern lab devic...

A troubleshooting guide to microplate-based assays

Tue, 01 Apr 2025 02:00:00 +0200

eBook 1.indd2 Today?s research often involves microplate readers as fast and reliable tools to push experiments forward. Whether it?s cell-based assays, high-throughput screening, or a host of molecular biology applications, reliable and meaningful data are crucial to support experiments. This fi rs...

Thermal Stability Technology Selection Guide for Biotherapeutic Drug Development

Fri, 25 Oct 2024 03:00:00 +0200

? 2024 TA Instruments. A division of Waters Corporation. All rights reserved. 1 Thermal Stability Technology Selection Guide for Biotherapeutic Drug Development A guide to automated biologics stability testing for ensuring product quality and supporting regulatory approvals Table of Contents Which D...

RNA Therapeutics: Ultrasensitive detection and absolute quantification with Droplet Digital PCR

Wed, 16 Oct 2024 04:00:00 +0200

A Droplet Digital? PCR eBook Visit bio-rad.com/RNA for more information. RNA: The Next Era in Therapeutic Development A dvances in therapeutic RNAs have exploded in recent years. These novel drugs have the potential to make personalized medicine a reality and, at the same time, make the term ?undrug...

How is High-Throughput Multi-Parameter Flow Cytometry used in Biopharma?

Wed, 16 Oct 2024 04:00:00 +0200

101-21 ZE5_Biopharma PDF-Evotec_010921.inddDesigned by Users for Users ? The ability of the ZE5 Cell Analyzer to deliver high-throughput screening with multiple parameters ensures the team are ready for future applications and experiments where instrument requirements will likely evolve.? Flow Cytom...

Guide to the Purification of Proteins and Antibodies Using Ion Exchange Chromatography

Wed, 28 Aug 2024 04:00:00 +0200

THEORETICAL AND PRACTICAL ASPECTS OF METHOD DEVELOPMENT The Selectivity Company 2 YMC Europe GmbH ? Sch?ttmannshof 19 ? D-46539 Dinslaken ? Phone +49 2064 427-0 ? Fax +49 2064 427-222 ? Email info@ymc.eu ? www.ymc.eu This Whitepaper ? ? is a practical guide to method development in preparative ion e...

Media formulation for biopharma

Tue, 21 Nov 2023 02:00:00 +0100

Get It Right First Time Increase Productivity Ensure Traceability M ed ia F or m ul at io n Gu id 3. Formulation Basics, Risks, and Solutions 5 3.1. The Basics of Formulation 5 3.2. Formulation Risks 6 3.4. Solutions for Accurate Formulation 10 4. Conclusions and Summary 17 The manufacture of bioph...

Asssessing comparability of CDV across most established automated cell counting platforms

Tue, 14 Nov 2023 02:00:00 +0100

3 Introduction Cell density and viability are critical process parameters in many cell culture applications for biologics development and production. Monitoring the health and growth of the culture is so important that numerous methods have been developed to meet this need. Automated cell counting h...

Bioreactor control system for precise fermentation in biopharma applications

Wed, 27 Sep 2023 04:00:00 +0200

e Gravimetric feed control uses a weight-based measurement to create an efficient method of controlling the flow of liquids into a bioreactor. Bioreactor feed control with balances can be easily achieved by accurately measuring weight to obtain a consistent and reproducible fermentation. This applic...

Fragment-Based Drug Discovery (FBDD) Using Novel Gradient Injections

Mon, 03 Apr 2023 02:00:00 +0200

Fragment-Based Drug Discovery (FBDD) Using Octet? SPR OneStep? and NeXtStep? InjectionsApplication Note Fragment-Based Drug Discovery (FBDD) Using Octet? SPR OneStep? and NeXtStep? Injections Eric L. Reese, Ph.D1, Aaron Martin2, David O. Apiyo, Ph.D2, and Stuart Knowling, Ph.D2 Sartorius, Fremont, C...

Optimizing Kinetics Assays to Prevent Avidity Effects

Mon, 03 Apr 2023 02:00:00 +0200

Application Note: Optimizing Kinetics Assays to Avoid Avidity EffectsApplication Note Optimizing Kinetics Assays to Avoid Avidity Effects Tim Heiseler1, PhD, Michael Metterlein2, Gail Calvert1, Philip Buckle1, Stuart Knowling1, PhD, Bob Dass1, PhD, Lisette Bronswijk-Deddens1, PhD 1 Sartorius Corpor...

Fast and Reproducible AAV Quantification

Mon, 03 Apr 2023 02:00:00 +0200

Octet? AAVX Biosensors for Rapid and Direct Quantitation of AAV CapsidsApplication Note Octet? AAVX Biosensors for Rapid and Direct Quantitation of AAV Capsids Yuanyuan Zhang, PhD, Ahmad Kour, Frederik Meierrieks, Nicole Laut, Benjamin Moritz Graf, PhD, Nazg?l Wagner, PhD, Ivan Krylov, PhD, Ling Zha...

A new generation, fully automated coagulation analyzer with a walk-away reagent management concept

Thu, 23 Mar 2023 02:00:00 +0100

Performance evaluation of the cobas? t?711 coagulation analyzer WHITE PAPER 1. Executive summary The cobas t 711 coagulation analyzer utilizes a walk-away reagent management (W.A.R.M.) concept and has demonstrated accurate and reproducible sample measurement in routine practice. We explored how the ...

Success with serial dilutions depends strongly on many factors

Thu, 02 Mar 2023 01:00:00 +0100

Guidelines for Any Protocol 1.1 Definition 2 1.3 Serial Dilutions in Biological Sciences 2 2 Factors Affecting Serial Dilutions and Building Optimal Working Ranges 3 2.1 Calculations 3 2.3 Dilutions Factors (DF) 4 2.4 Analyte (Stock Solution) 4 2.5 Inefficient and Incomplete Mixes 5 2.6 Det...

A Fast Routine Test – Ensures Trusted Moisture Results

Wed, 01 Mar 2023 02:00:00 +0100

A Fast Routine Test Ensures Trusted Moisture Results Regular verification of measuring devices is essential to ensure valid results and maintain quality. Routine calibration and preventative maintenance of moisture analyzers should be performed by a qualified service engineer, but additional perform...

How to enhance lab safety by lean principles

Wed, 01 Mar 2023 02:00:00 +0100

2. Establishing and Maintaining Order Using the 5S Method 3. Focusing on “The Sixth S”: Safety 4. Results of “5S +1” Implementation 5. Summary: Applying 5S in the Lab Appendix: Glossary of Terms Lean Lab Includes Lab Safety Ensure Accuracy, Safety and Efficiency Lean principles help to systematicall...

Protect the quality and reliability of your research images for publication

Tue, 13 May 2025 02:00:00 +0200

In this webcast Cytiva and STM talk about maintaining integrity of images in publications and ensuring the integrity of your academic research We will cover: Concerns associated with image integrity in academic research; Why it matters and how STM plays a part in maintaining integrity of your re...

Challenge analytical complexity – Biacore™ SPR systems

Tue, 13 May 2025 02:00:00 +0200

This webinar presents the utility of Biacore systems at all stages of the process from selection of first candidates to clinical lead. Showing that a combination of Biacore instruments, software, sensor chips, and kits support the setup of screening and characterization assays, shortenstreamline the...

How You Can Make Your Certificate Approval Fast and Efficient

Mon, 12 May 2025 02:00:00 +0200

Discover how Tenthpin Intelligent Certificate VerificAItion (T/ICV) speeds up and enhances certificate approvals using AI and Large Language Models. T/ICV automates handling, matching, and verification in under 5 minutes per document; boosting transparency and reducing errors. Watch our webinar to s...

Make Your QM 6x More Efficient With an Integrated, AI-Powered, End-to-End Solution

Mon, 12 May 2025 02:00:00 +0200

Rising regulatory demands and paper-based Quality Management processes create delays and frustration. Traditional ERP systems fall short, while specialized tools fragment the IT landscape. Tenthpin Intelligent Quality Suite is your one-stop shop for AI-powered Quality Management solutions, tailored ...

Integrated Quality Control and Quality Assurance Process with Tenthpin Quality Management Evolved

Mon, 12 May 2025 02:00:00 +0200

Discover how to digitize and optimize your Quality Management with smart features like the QC Sample Cockpit, QC Record Inspection Results, QA Checks at Usage Decision, and QA Batch Master Management. To streamline your quality control and assurance processes with one integrated solution, watch our ...

Maximizing Accuracy, Reducing Errors in Titration & Weighing

Thu, 08 May 2025 02:00:00 +0200

Titration is essential in quality control and R&D, with accuracy and precision crucial for process efficacy and product quality. Weighing, the first stage of analysis, significantly impacts result reliability. Join the webinar to explore factors affecting titration accuracy and precision, weighing f...

You're Now Connected: Prepare Your Lab for the Future

Thu, 08 May 2025 02:00:00 +0200

Digitalization is crucial for success in modern labs, enhancing data accuracy and research efficiency. This webinar explores data integrity and lab connectivity. Discover lab products like Sartorius balances with Ingenix data management, advanced pipettes, and calibration solutions ensuring integrat...